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Michael W Fried Selected Research

Flavonolignans

12/2011Differences in the disposition of silymarin between patients with nonalcoholic fatty liver disease and chronic hepatitis C.
4/2010Silymarin ascending multiple oral dosing phase I study in noncirrhotic patients with chronic hepatitis C.
9/2008The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic Fatty liver disease and correlates with plasma caspase-3/7 activity.

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Michael W Fried Research Topics

Disease

53Chronic Hepatitis C
01/2022 - 09/2002
43Infections
12/2021 - 09/2002
29Fibrosis (Cirrhosis)
01/2022 - 02/2003
29Hepatitis C
01/2021 - 10/2002
12Liver Diseases (Liver Disease)
01/2022 - 10/2002
7Chronic Hepatitis B
01/2022 - 06/2005
5Hepatocellular Carcinoma (Hepatoma)
01/2022 - 05/2018
5Substance-Related Disorders (Drug Abuse)
01/2020 - 10/2011
5Virus Diseases (Viral Diseases)
01/2018 - 09/2002
4Non-alcoholic Fatty Liver Disease
01/2022 - 09/2008
4Liver Cirrhosis (Hepatic Cirrhosis)
10/2017 - 08/2012
3Hepatitis
12/2021 - 02/2012
3Alcoholic Fatty Liver
12/2021 - 01/2019
3Coinfection
07/2015 - 08/2006
3Anemia
10/2010 - 11/2002
3Body Weight (Weight, Body)
10/2008 - 09/2002
2End Stage Liver Disease
01/2020 - 03/2004
2Hepatitis B
05/2019 - 07/2005
2Portal Hypertension
05/2018 - 11/2015
2Fatigue
08/2014 - 11/2002
2Hemolytic Anemia
10/2010 - 08/2008
2Neutropenia
08/2008 - 11/2002
2Hemorrhage
03/2005 - 10/2002
2Acute Liver Failure (Fulminant Hepatic Failure)
08/2004 - 10/2002
2Human Influenza (Influenza)
11/2002 - 09/2002
1Cardiovascular Diseases (Cardiovascular Disease)
01/2021
1Chronic Renal Insufficiency
01/2021
1COVID-19
01/2021
1Obesity
01/2021
1Alcoholism (Alcohol Abuse)
01/2020
1Reinfection
01/2016
1HIV Infections (HIV Infection)
10/2014
1Disease Progression
10/2014
1Headache (Headaches)
08/2014
1Exanthema (Rash)
08/2014
1Hyperbilirubinemia
12/2013
1Persistent Infection
09/2011

Drug/Important Bio-Agent (IBA)

39Ribavirin (Virazole)FDA LinkGeneric
10/2021 - 09/2002
35Antiviral Agents (Antivirals)IBA
01/2022 - 02/2003
23InterferonsIBA
05/2017 - 10/2002
11SofosbuvirIBA
12/2019 - 05/2014
11peginterferon alfa-2a (Pegasys)FDA Link
10/2008 - 09/2002
9RNA (Ribonucleic Acid)IBA
05/2019 - 10/2002
7SilymarinIBA
01/2019 - 09/2008
6sofosbuvir drug combination ledipasvirIBA
01/2022 - 05/2014
6Alanine Transaminase (SGPT)IBA
01/2020 - 08/2006
6AlbuminsIBA
01/2020 - 02/2015
6Pharmaceutical PreparationsIBA
01/2018 - 06/2003
5Hepatitis B Surface Antigens (HBsAg)FDA Link
01/2021 - 06/2005
5DNA (Deoxyribonucleic Acid)IBA
01/2020 - 06/2005
5SimeprevirIBA
01/2018 - 12/2013
4Hepatitis B e AntigensIBA
01/2021 - 06/2005
4BilirubinIBA
01/2020 - 12/2016
4ledipasvirIBA
11/2018 - 05/2014
4Protease Inhibitors (Protease Inhibitor)IBA
01/2018 - 02/2014
4telaprevirIBA
04/2015 - 09/2011
4Interferon alpha-2 (Roferon-A)FDA Link
08/2014 - 09/2002
3NucleotidesIBA
09/2015 - 05/2014
3Silybin (Lagosa)IBA
12/2011 - 09/2008
3FlavonolignansIBA
12/2011 - 09/2008
2glecaprevir and pibrentasvirIBA
12/2019 - 01/2017
2daclatasvirIBA
01/2018 - 06/2015
2paritaprevirIBA
10/2017 - 11/2015
2ombitasvirIBA
10/2017 - 11/2015
2dasabuvirIBA
10/2017 - 11/2015
2Ritonavir (Norvir)FDA Link
10/2017 - 11/2015
2N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA
02/2015 - 08/2014
2Interferon-alpha (Interferon Alfa)IBA
06/2005 - 07/2003
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2022
1Oxidoreductases (Dehydrogenase)IBA
01/2022
1Phosphotransferases (Kinase)IBA
01/2021
1remdesivirIBA
01/2021
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
01/2021
1L 644711 (B-3(+))IBA
12/2019
1Immunoglobulin G (IgG)IBA
05/2019
1Immunoglobulin M (IgM)IBA
05/2019
1nasIBA
01/2019
1AntioxidantsIBA
01/2019
1Serum AlbuminIBA
10/2017
1trichostatin A (A 300)IBA
01/2017
1Proton Pump InhibitorsIBA
12/2016
1Biomarkers (Surrogate Marker)IBA
11/2015
1N 30IBA
06/2015
1CreatinineIBA
02/2015
1Cytochrome P-450 CYP3AIBA
10/2014
1Peptide Hydrolases (Proteases)FDA Link
10/2014
1HCV NS3-4A Protease InhibitorsIBA
08/2014
1Transaminases (Aminotransferases)IBA
12/2013
1asunaprevirIBA
01/2013
1Viral RNAIBA
02/2012

Therapy/Procedure

55Therapeutics
01/2022 - 10/2002
17Liver Transplantation
01/2021 - 10/2002
3Drug Tapering
10/2010 - 11/2002
2Aftercare (After-Treatment)
12/2019 - 12/2016
2Duration of Therapy
02/2016 - 11/2015
1Drug Therapy (Chemotherapy)
12/2021
1Artificial Respiration (Mechanical Ventilation)
01/2021
1Immunotherapy
01/2021
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
11/2019
1Art Therapy
07/2015